Eyes will also be on early season high flyers Stellenbosch who will be looking to extend their unbeaten run to eleven matches when they host AmaZulu who have improved significantly in recently.
At the bottom of the standings, basement side Marumo Gallants, who are under new coach Dan Malesela, will be looking for their first win of the season when they take on SuperSport United.
Other struggling teams at the bottom TS Galaxy, Chippa, who have former player Kurt Lentjies in caretaker charge after the suspension of Gavin Hunt, Swallows and Baroka will also be looking for morale boosting wins this weekend.
Golden Arrows VS Orlando Pirates
Orlando Pirates will be looking to get back to winning ways when they visit highly unpredictable Golden at the Princess Magogo Stadium after they lost 2-1 to Kaizer Chiefs in the Soweto derby before the international break.
Abafana Bes’thende, who have endured mixed results at home, have ambitions of their own following a recent run of two losses and draws that has derailed their movement into the top half of the table.
Pick: Pirates Wins by 1.28 at BetXChange
Stellenbosch VS AmaZulu
Stellenbosch, who battled relegation for the better part of last season, are undoubtedly the surprise packages of this campaign so far as they are sitting second from the top with 20 points from ten matches.
Together with log-leaders Mamelodi Sundowns, they are yet to be beaten in the league this season but improving AmaZulu have what is takes to rise to the occasion and hand them their first defeat of the season.
Pick: Stellenbosch Wins by 1.46 at BetXChange
Baroka VS Chippa United
This is the battle of the struggling teams but slight advantage will be with Baroka who have only lost once at home this season after four matches and they are desperate for their first victory in five matches.
Chippa United have travelled to Peter Mokaba Stadium in Limpopo with former midfielder Kurt Lentjies in caretaker charge after the suspension of coach Gavin Hunt and players will be looking to impress the new man in charge.
Pick: Baroka Wins by 1.15 at BetXChange
SuperSport United VS Marumo Gallants
After a good start to the campaign, SuperSport United recently suffered two successive defeats to Kaizer Chiefs and Royal AM but they bounced back with a win over TS Galaxy before the break.
They are up against bottom of the log and Marumo Gallants who will be looking for their first win of the season under new coach in Dan Malesela who arrived at the club this week to try and revive their campaign.
Pick: SuperSport Wins by 0.63 at BetXChange
Cape Town City VS Mamelodi Sundowns
This is without doubt biggest match of the weekend and defending champions Mamelodi Sundowns go into it looking to register their eight successive win and to go thirteen matches without conceding a goal.
On the other hand, Cape Town City are looking for three points to force their way into the top eight bracket on the log and also to avenge the MTN8 final loss they suffered at the hands of the Brazilians in Durban recently.
Pick: Sundowns Wins by 0.73 at BetXChange
Sekhukhune United VS Royal AM
This is the battle of the rookies who have surpassed expectations in the paid ranks as they are mixing with the early pacesetters so early in the season after they impressively started heir campaigns.
Royal AM go into this match fourth on the table with eighteen points from ten matches while Sekhukhune United sitting below them on fifth place seventeen points from the same number of games.
Pick: Royal AM Wins by 1.74 at BetXChange
TS Galaxy VS Swallows
These are the other two struggling teams who are sitting side by side on wrong side of the DStv Premiership standings where Swallows eight points and TS Galaxy have seven to show for their troubles.
They go into this match with Swallows having lost two and draw three of their last five matches and TS Galaxy boasting one victory and four losses to sit second from the bottom of the standings.
Pick: Swallows Wins by 1.71 at BetXChange
Maritzburg United VS Kaizer Chiefs
The last bit of action for this weekend sees Kaizer Chiefs at the Harry Gwala Stadium in Pietermaritzburg where Amakhosi will be looking to register their second away win in succession.
Their mission for three points is not going to be an easy one as Maritzburg United have shown some improvement over their last five matches where they have registered one win, two draws and losses.
Pick: Chiefs Wins by 1.39 at BetXChange
