They are battling it out to finish second on the log and book the remaining Caf Champions League spot and AmaZulu are front runners to claim that position even though they are under pressure from Arrows and Pirates.
As the season enters the penultimate stage on Wednesday afternoon, interest will also be firmly fixed on the race for third spot with fifth-placed Swallows and sixth-placed SuperSport United involved in that hotly race with AmaZulu, Arrows and Pirates.
There is also an intriguing race to finish for the top eight which is contested by Kaizer Chiefs, Bloemfontein Celtic, Baroka TS Galaxy and Cape Town City to see who will qualify for the MTN8 competition next season.
At the foot of the table, the battle Black Leopards, Chippa United, Stellenbosch, Tshakhuma Tsha Madzivhandila (TTM), Maritzburg United involved in their battle to avoid automatic relegation or the dreaded promotion and relegation play-offs.
Cape Town City vs Black Leopards
Black Leopards, who have been sitting at the foot of the table for most of the campaign, will almost certainly be relegated to the National First Division (NFD) if they drop all the three points against Cape Town City at the Cape Town Stadium.
At the same time, Cape Town City, who have a new coach in the form of Eric Tinkler, will significantly boost their chances finishing the season in the top eight.
Pick: Cape Town City Wins at 0.77 at BetXChange
Tshakhuma Tsha Madzivhandila (TTM) vs Chippa United
TTM, who have been through a roller coaster of a season following their poor start, have avoided automatic relegation but they have a tough job at hand to ensure that they also avoid getting dragged into tricky promotion and relegation play-offs.
Their mission is not going to be an easy one as they are up against the Chippa United side that has relegation worries of their own as they are second from the bottom with two matches remaining in the season.
Pick: TTM Wins at 1.20 at BetXChange
Bloemfontein Celtic vs Mamelodi Sundowns
There is nothing much but pride at stake for Mamelodi Sundowns in this match as they have already won the league with three matches to spare last week for what is their fourth championship success in four successive seasons.
For coach John Maduka and his men, this is a must win match as three points will significantly enhance their faint chances of finishing the season in the top eight to make up for what has been a frustrating season.
Pick: Sundowns Wins at 0.87 at BetXChange
SuperSport United vs Maritzburg United
A win for SuperSport United will almost certainly see them secure a place in the top eight but to get those three points they must overcome Maritzburg United who have relegation fears of their own going into this match.
Pick: SuperSport Wins at 1.18 at BetXChange
Baroka vs Orlando Pirates
Baroka, who have managed three draws, one win and one loss in their last five matches, are determined to book a place in the top eight after what has been a relatively improved season where they are not involved in the relegation battle.
Baroka will fancy their chances against Pirates, who are fragile after they lost their last match to TS Galaxy at the weekend that has left their chances of qualifying for the Caf Confederation Cup not in their hands.
Pick: Pirates Wins at 0.87 at BetXChange
Stellenbosch v TS Galaxy
Stellenbosch will ensure safety with three home points but they are not going to have things their own way as TS Galaxy, who will be motivated by their win over Orlando Pirates at the weekend, want to cement a top eight position.
Pick: Stellenbosch Wins at 1.51 at BetXChange
AmaZulu vs Swallows
AmaZulu will secure second spot finish and a place in the Caf Champions League to join league champions Mamelodi Sundowns in continental football next season if they beat league’s draw masters Swallows at Kings Park Stadium.
On the other hand, Swallows will also be looking for three points as they can still overtake Orlando Pirates and Golden Arrows to finish third on the log and qualify for the Confederation Cup.
Pick: AmaZulu Wins at 1.67 at BetXChange
Kaizer Chiefs vs Golden Arrows
Kaizer Chiefs are smarting from their disappointing 2-1 loss to basement side Black Leopards last week that has left them sitting dangerously sixth from the bottom of the standings and it cost former coach Gavin Hunt his job.
They are up against a determined Arrows side that has intentions of finishing third and qualify for the Confederations Cup next season.
Pick: Chiefs Wins at 1.40 at BetXChange