If the Boks victory on what is expected to be hostile Twickenham, the world champions will wrap up a successful season where they produced nine victories after 13 Test matches they took part in.
The last time the Springboks beat England in London was in 2014, when they edged their hosts 31-28 but they have won three of their last six outings against their northern hemisphere arch-rivals.
The most recent win by the Springboks over England was the Rugby World Cup final in Yokohama in 2019 where the South Africans emerged 32-12 victors.
Andrew Brace (Ireland) has been appointed the match referee and he will be assisted by Angus Gardner (Australia) and Frank Murphy (Ireland), while his Irish compatriot Brian MacNeice will be on Television Match Official duty.
England VS South Africa
Blind-side flanker Courtney Lawes has been named by England coach Eddie Jones as captain of the side for the hugely anticipated Test.
Number eight Tom Curry and outside centre Henry Slade will be vice-captains as England will be looking to stop South Africa from winning their third match in a row.
Jamie Blamire will start as hooker, with props Bevan Rodd and Kyle Sinckler joining him in the front row, locks Maro Itoje and Jonny Hill complete the tight five and Sam Underhill is at open-side flanker.
Joe Marchant returns to the side on the right wing, Jonny May is on the left wing and Freddie Steward is at full back, Manu Tuilagi is at inside centre, Marcus Smith is at fly half and the side’s most capped-player Ben Youngs is at scrum half.
Hooker Nic Dolly could make his England debut, as he is named as a finisher alongside Joe Marler, Will Stuart, Charlie Ewels, Sam Simmonds, Alex Dombrandt, Raffi Quirke and Max Malins.
Springbok coach Jacques Nienaber named Handré Pollard and Cobus Reinach in a fresh halfback pairing and recalled Lood de Jager at lock in three changes to his starting team for this match.
Flyhalf Pollard, scrumhalf Reinach and De Jager have been drafted into the starting line-up in rotational switches which sees Elton Jantjies and Herschel Jantjies join utility back Franco Mostert among the replacements in other changes to the match-day squad that defeated Scotland 30-15 at Murrayfield last week.
The Boks have stuck with the same match-day 23 as the one that beat Scotland and key against England is going to the strength of the vaunted replacements who are better known as the “Bomb Squad”.
It is also worth noting that the Springboks have been down at half-time in six consecutive Tests since September and they went on to win three of them.
In 25 matches since November 2018, they have outscored or equalled their opponents in the second half on 23 occasions.
Pick: South Africa Wins by 0.80 at BetXChange
